Uganda is in the midst of a demographic tsunami with its population doubling every 16 years. Uganda’s systems must be transformed to rapidly increase agricultural productivity, curb accelerating environmental degradation, alleviate the burden of communicable diseases, and educate and train a more and increasingly younger population of Ugandans that need to be both more productive and more involved as citizens. The rapidly growing population exacerbates high levels of youth unemployment and amplifies pressures on social, natural and other resources. Inadequately addressed, these issues will lead to a growing number of marginalized Ugandans without access to public or other services; lacking resilience to shocks and stresses; and held back from their progress; and, thus, unable to realize their individual or collective potential.